Key Gaps in Current Environmental Hygiene Practices
Despite advances in infection prevention, several persistent vulnerabilities remain in how healthcare environments address environmental contamination, particularly related to floors, footwear, and transitional spaces.
Underestimation of Floors and Footwear as Vectors
Floors and shoe soles are becoming broadly recognized as significant reservoirs for pathogenic microorganisms, including MRSA, VRE, Clostridioides difficile, and multidrug-resistant Gram-negative organisms (Limper et al., 2024; Tyski et al., 2025; Greene, 2020). Despite this, floors are still frequently classified as "low-touch" surfaces and therefore receive less frequent and less rigorous disinfection. Their low-touch classification fails to account for the constant redistribution of floor-borne organisms via foot traffic, equipment movement, and airflow, creating a persistent pathway for cross-contamination.
Despite routine exposure to contaminated surfaces, footwear is rarely subjected to systematic decontamination protocols in healthcare settings, even in high-risk clinical areas.
Limitations of Existing Footwear Decontamination Practices
For decades now, research has been finding footwear and floor hygiene practices are often inadequate, and a lack of practical and effective controls has hindered progress to reduce the risk for microbial contamination of organisms from these surfaces (Donskey, 2023). Agarwal et al. (2002) found that most OR shoes carried bacteria and that standard cleaning methods were insufficient, leading the authors to recommend automated cleaning approaches. Additional research shows that even dedicated operating room shoes accumulate significant microbial contamination, and that visual cleanliness does not correlate with microbiological safety (Tateiwa et al., 2020).
Moreover, facilities that allow the same footwear to be worn across clean and semi-restricted zones experience increased airborne particle counts during movement, suggesting enhanced dispersal of contaminants into critical spaces. This undermines the effectiveness of other infection prevention measures.
Gaps in Floor Disinfection Practices
Floor disinfection practices also suffer from inconsistent execution. Studies have found that automated dispensing systems frequently deliver incorrect concentrations of disinfectant (sometimes none at all) and in-use mop solutions may contain insufficient or inappropriate chemistry (Cadnum et al., 2025). Despite this, escalation to higher-level disinfectants is often reserved only for visible contamination or known outbreaks, overlooking the routine microbial burden present on floor surfaces.
Opportunity for Advanced Footwear Decontamination Technologies
A device that uses UV-C and ozone to sanitize shoe soles
Key Takeaway
Enhances traditional hygiene protocols
References
- Tyski, S., Burza, M., & Laudy, A. (2025). Microbiological Contamination of Medicinal Products - Is It a Significant Problem?. Pharmaceuticals, 18. https://doi.org/10.3390/ph18070946
- Limper, H., Sier, A., Warye, K., Spencer, M., Graves, P., & Edmiston, C. (2024). A Review of the Evidence on the Role of Floors and Shoes in the Dissemination of Pathogens in a Healthcare Setting. Surgical Infections. https://doi.org/10.1089/sur.2023.194
- Donskey, C.J. (2023). Update on potential interventions to reduce the risk for transmission of health care-associated pathogens from floors and sinks. American Journal of Infection Control, Volume 51, Issue 11, Supplement, Pages A120-A125. https://doi.org/10.1016/j.ajic.2023.03.009
- Agarwal, M., Hamilton-Stewart, P., & Dixon, R. (2002). Contaminated operating room boots: the potential for infection. American Journal of Infection Control, 30(3), 179-83. https://doi.org/10.1067/mic.2002.119513
- Cadnum, J., Kaple, C., Saade, E., Ray, A., & Donskey, C. (2025). Evaluation of automated disinfectant dispenser systems in 6 hospitals demonstrates a need for improved monitoring to ensure that correct disinfectant concentrations are delivered. Open Forum Infectious Diseases, 12. https://doi.org/10.1093/ofid/ofae631.459
- Tateiwa, T., Masaoka, T., Ishida, T., Shishido, T., Takahashi, Y., & Yamamoto, K. (2020). Impact of surgical clothing and footwear on operating room contamination during standstill and intraoperative stepping motion. Journal of Orthopaedic Surgery, 28. https://doi.org/10.1177/2309499020976232
- Greene, C. (2020). Efficacy of Ultraviolet Light Coupled with Ozone as a Germicidal Against Eight Healthcare Associated Environmental Pathogens.
Application Limits
UVZone® treats the undersides of shoes during an activated treatment cycle. It does not continuously treat the room, the facility, or the footwear after the user steps off the station.
If footwear requires physical cleaning, that cleaning step remains necessary. If your procedure requires chemical treatment, shoe covers, dedicated footwear, hand hygiene, personal protective equipment, environmental cleaning, sanitation, traffic controls, or another facility control, that requirement remains in place until the responsible facility team approves a change.
UVZone® is intended to complement a broader contamination-control, hygiene, infection-prevention, or biosecurity program. It does not independently establish compliance or guarantee a facility-specific result.
Third-Party Lab Verified Efficacy. Selected results shown. Full laboratory reports are available upon request. Testing conducted from 2019 through 2022.
Efficacy claims based on independent laboratory testing. Results may vary based on application conditions. Patho3Gen technology is designed for environmental surface sanitation and is not intended to diagnose, treat, cure, or prevent any disease. Always follow manufacturer guidelines and applicable regulations.